Description
Current research suggests that tesofensine works in the following ways:
As a triple monoamine reuptake inhibitor (SNDRI), tesofensine influences key neurotransmitters in the brain:
- Increases neurotransmitter levels: It boosts the availability of serotonin, dopamine, and norepinephrine in the brain.
- Reduces appetite: By affecting the brain’s appetite and reward centers, it decreases food cravings and promotes a feeling of fullness.
- Increases energy expenditure: Tesofensine may also increase the body’s resting metabolism, leading to greater calorie burn.
- Combats weight rebound: Studies have shown it may help prevent weight regain, a common issue after diet-induced weight loss.



